Chemistry and Pharmacological Activities of Pyrazole and Pyrazole Derivatives: A Review
نویسندگان
چکیده
منابع مشابه
Synthesis and Pharmacological Activities of Pyrazole Derivatives: A Review.
Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities. The presence of this nucleus in pharmacological agents of diverse therapeutic categories such as celecoxib, a potent anti-inflammatory, the antipsychotic CDPPB, the anti-obesity drug rimonabant, difenamizole, an analgesic, betazole, a H2-recept...
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*Corresponding author E mail: [email protected] J. Pharm. BioSci. 3(2013) 114-123 Abstract Pyrazole is five membered heterocyclic rings which is versatile lead compound for designing potent bioactive agent. The interesting groups of this compound has diverse biological activities such as antimicrobial, anti-inflammatory, anticancer, analgesic, anticonvulsant, anthelmintic, antioxidant an...
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Pyrazole is associated with wide range of biological properties. These ring systems are incorporated into drugs used for AIDS, cancer, anti-viral treatment etc. Pyrazole derivatives are well established in the literature as important biologically active compounds. They have a long history of application in agrochemicals and pharmaceutical industry as herbicides and active pharmaceuticals. Pyraz...
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In search of bioactive molecules in the class of functionally substituted heterocyclic compounds, we synthesized some new N-(1-methyl-1H-pyrazole-4-carbonyl)thiourea derivatives and evaluated their analgesic and sedative effects. The obtained compounds were characterized by elemental analysis, IR and NMR spectroscopic analyses and evaluated for their analgesic and sedative effects.
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutical Sciences Review and Research
سال: 2020
ISSN: 0976-044X
DOI: 10.47583/ijpsrr.2020.v65i01.030